Fecal Microbiome Composition in Healthy Adults in Ghana

Recent studies have indicated an association between gut microbiome composition and various disorders, including infectious diseases. The of the differs among ethnicities countries, possibly resulting in diversified interactions host immunity microbiome. Characterization baseline healthy people is essential step for better understanding biological associated with individual populations. However, data on gut/fecal not been accumulated individuals West Africa. In present study, we examined fecal adults Ghana. Toward this, 16S rRNA gene libraries were prepared using bacterial fractions derived from 55 Ghanaian adults, which then subjected to next-generation sequencing. was dominated by Firmicutes (Faecalibacterium, Subdoligranulum, Ruminococcaceae UCG-014), Proteobacteria (Escherichia-Shigella Klebsiella), Bacteroidetes (Prevotella 9 Bacteroides), consistent previous observations African cohorts. Further, our analysis revealed differences a lower diversity cohort compared those reported non-African countries. This first study describe substantial obtained high-throughput metagenomic tools samples may provide valuable basis determining progression diseases